Inhibition of apoptosis by Nur77 through

nuri77The role of Nur77 in celastrol-induced mitophagy was illustrated by reduction of autophagic mitochondria (from 12.20 to 0.02%) and diminished COXII degradation in HeLaOrphan nuclear receptor Nur77 has been reported to be implicated in a diverse range of metabolic processes, including carbohydrate metabolism and lipid metabolism.