Discovery of a novel exceptionally potent and orally active Nur77

nuri77Fure 1.Nur77 expression level in in vitro generated murine dendritic cells (DCs).(A) Plasmacytoid DCs (pDCs) and conventional DCs (cDCs) were sorted from FLT3LNur77 responds to a wide range of physiological molecules and stimuli. 4, 14 These snals quickly induce Nur77 expression and stimulate its transcriptional activity; Nur77