The orphan receptor Nur77 binds cytoplasmic LPS to

nuri77The role of Nur77 in celastrol-induced mitophagy was illustrated by reduction of autophagic mitochondria (from 12.20 to 0.02%) and diminished COXII degradation in HeLaNur77 was orinally identified by differential hybridization screening as a nerve growth factor–induced gene in pheochromocytoma cells. 3 The domain structure of Nur77